The Open Bioinformatics Journal

Volume 18, 2025

Early View
PUBLISHED ARTICLES


RESEARCH ARTICLEDOI: 10.2174/0118750362408821250821062122 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Identification of Diagnostic and Prognostic Biomarkers in Nasopharyngeal Carcinoma using Integrated Transcriptomics and Elastic Net Survival Analysis Volume: 18 (2025): e18750362408821 [Electronic Publication Date: August 23, 2025] Nur Aziz, Laily Rahmawati and Jae Youl Cho Abstract View Fulltext HTML PDF Download ePub
REVIEW ARTICLEDOI: 10.2174/0118750362383096250523051202 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. A Comprehensive Review of Blood Malignancy Detection in Microscopic Blood Cell Images Utilizing Complete Leukocyte Count Data Volume: 18 (2025): e18750362383096 [Electronic Publication Date: July 25, 2025] Yogesh Lohumi, Durgaprasad Gangodkar, Manoj Diwakar, Prabhishek Singh, Salman Akhtar and Punit Kumar Singh Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362401268250715144626 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Tool FindCrispr: An Accurate Identification of Crisprs Volume: 18 (2025): e18750362401268 [Electronic Publication Date: July 21, 2025] Chunmei Wang Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362387304250716055022 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Convolutional Neural Network-based Multi-Classification of Skin Disease with Fine-Tuned ResNet50 and VGG16 Volume: 18 (2025): e18750362387304 [Electronic Publication Date: July 21, 2025] Dimple Kapoor, Deepali Gupta, Yonis Gulzar, Mohannad Alkanan, Mohammad Shuaib Mir, Arjumand Bano Soomro, Mudita Uppal and R. Reshma Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362393187250710204910 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. A Mathematical Model for Predicting Nearest Neighbor in Diabetes Diagnosis Volume: 18 (2025): e18750362393187 [Electronic Publication Date: July 16, 2025] Arwa Zabian and Omar H. Abu El Haija Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362370697250630063814 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. A Review of Deep Learning-based Multi-modal Medical Image Fusion Volume: 18 (2025): e18750362370697 [Electronic Publication Date: July 04, 2025] Shailesh Bhosekar, Prabhishek Singh, Deepak Garg, Vinayakumar Ravi and Manoj Diwakar Abstract View Fulltext HTML PDF Download ePub
CORRIGENDUMDOI: 10.2174/01187503623561191405202501 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Corrigendum to: Advanced Machine Learning Techniques for Prognostic Analysis in Breast Cancer Volume: 18 (2025): e187503621405202501 [Electronic Publication Date: June 05, 2025] Kiran Puttegowda, Anil Kumar D, Vinayakumar Ravi, V Veeraprathap, Pradeep Ravi, G R Yathiraj and Sunil Kumar D S View Fulltext HTML PDF
RESEARCH ARTICLEDOI: 10.2174/0118750362383003250527080758 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. In Silico Study of Dibenzylidene Cyclohexanone-Based Curcumin Analogs as Potential Inhibitors of Breast Cancer Receptor Proteins Volume: 18 (2025): e18750362383003 [Electronic Publication Date: June 02, 2025] Ranti Kamila Habibie and Ritmaleni Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362364938250520114456 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Characterizing and Evaluating Cell Specialization Through the Gini Index of Gene Expression: A TCGA Normal vs. Tumor Case Study Volume: 18 (2025): e18750362364938 [Electronic Publication Date: May 29, 2025] Fabio Cumbo and Daniele Santoni Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362382139250502100340 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Enhancing Early Diagnosis of Type II Diabetes through Feature Selection and Hybrid Metaheuristic Optimization Techniques Volume: 18 (2025): e18750362382139 [Electronic Publication Date: May 09, 2025] Sunil Upadhyay and Yogesh Kumar Gupta Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362380269250502062754 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. iCDRET: A Dynamic Cyber Risk Estimation Technique for Intelligent Cyber-physical Systems in PCS Volume: 18 (2025): e18750362380269 [Electronic Publication Date: May 09, 2025] Swati Devliyal, Himanshu Rai Goyal and Sachin Sharma Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362370719250411094442 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. A Dual CT Image Denoising Approach using Guided Filter and method-based Noise in the NSST Domain Volume: 18 (2025): e18750362370719 [Electronic Publication Date: April 25, 2025] Swapna Katta, Prabhishek Singh, Deepak Garg, Vinayakumar Ravi and Manoj Diwakar Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362380098250416071630 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Balancing Accuracy and Recall in Hebbian and Quantum-inspired Learning Models Volume: 18 (2025): e18750362380098 [Electronic Publication Date: April 25, 2025] Theodoros Kyriazos and Mary Poga Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362357726250410070525 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Patterns of Transposable Element Distribution around Chromatin Ligation Points Revealed by Micro-C Data Analysis Volume: 18 (2025): e18750362357726 [Electronic Publication Date: April 16, 2025] Alexandr V. Vikhorev, Michael M. Rempel, Oksana O. Polesskaya, Ivan V. Savelev, Alexandre A. Vetcher and Max V. Myakishev-Rempel Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362369549250327052654 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Exploring Camptothecin Derivatives from the Chinese Tree of Camptotheca acuminata as Breast Cancer Protease Inhibitors: Insights from Multi-Scale Computational Analysis Volume: 18 (2025): e18750362369549 [Electronic Publication Date: April 10, 2025] Zena Abdul-Ameer Mahdi, Batool Shakir Abed Almjalawi, Mollah Naimuzzaman, Mahabub Hasan, Farah Tareq Al-Alaq, Hussein O.M. Al-Dahmoshi, Ajoy Kumer, Noor S.K. Al-Khafaji, Sarah Alwan Malik Al-Yasiri and Morteza Saki Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362365832250317180036 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Bioinformatics and System Biology Approach to Identifying the Influence of COVID-19 on Patients with Osteoarthritis Volume: 18 (2025): e18750362365832 [Electronic Publication Date: April 07, 2025] Zhu. Jie, Li Xiong, Zhiming Cheng and Yuan Zhang Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362371740250316120413 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. In Vitro and In Silico Study of Nardostachys Jatamansi DC for Cognitive Impairment Related Conditions Volume: 18 (2025): e18750362371740 [Electronic Publication Date: April 03, 2025] Shamshad Ather, Kapil Singh Thakur, Yogesh Patil, Amita Kirar, Poonam Patil, Sunita Singh and Mansee Thakur Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362370483250314042749 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Evaluating Deep Learning Models for Object Detection in Kirby-Bauer Test Result Images Volume: 18 (2025): e18750362370483 [Electronic Publication Date: April 03, 2025] Hoang Bach Nguyen, Thanh Luan Phan and Thi Khanh Linh Nguyen Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362361900250312054436 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Predictive Analysis of Parkinson's Disease Using Machine Learning Volume: 18 (2025): e18750362361900 [Electronic Publication Date: March 27, 2025] Harshitha Kamal Kannan, M R Pooja and Vinayakumar Ravi Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362370187250307055547 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. In silico Evaluation of Potential Bioactive Peptides of Phycoerythrins from Selected Rhodophytes Volume: 18 (2025): e18750362370187 [Electronic Publication Date: March 25, 2025] Kazi Nazira Sharmin, W. Lindsey White and Kevin Lee Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362358232250212111157 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Enhancing Brain Tumor Segmentation using Berkeley Wavelet Transformation and Improved SVM Volume: 18 (2025): e18750362358232 [Electronic Publication Date: February 19, 2025] Sandeep Kumar, Jagendra Singh, Prabhishek Singh, Manoj Diwakar, Indrajeet Gupta, Vinayakumar Ravi and Siti Sarah Maidin Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362355440250203115520 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Deep Learning-based Staging of Throat Cancer for Enhancing Diagnostic Accuracy Through Multimodal Data Integration Volume: 18 (2025): e18750362355440 [Electronic Publication Date: February 07, 2025] Jagendra Singh, Jaideep Kumar, Vinayakumar Ravi, Prabhishek Singh, Siti Sarah Maidin, Manoj Diwakar and Indrajeet Gupta Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362349305250131062510 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Ensemble-based Heart Disease Diagnosis (EHDD) using Feature Selection and PCA Extraction Methods Volume: 18 (2025): e18750362349305 [Electronic Publication Date: February 06, 2025] V. Vinodhini, B. Sathiyabhama, S. Vidhushavarshini, Vinayakumar Ravi and R. Shashidhar Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362356119250121072106 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Advanced Machine Learning Techniques for Prognostic Analysis in Breast Cancer Volume: 18 (2025): e18750362356119 [Electronic Publication Date: January 28, 2025] Kiran Puttegowda, Anil Kumar D, Vinayakumar Ravi, V Veeraprathap, Pradeep Ravi, G R Yathiraj and Sunil Kumar D S Abstract View Fulltext HTML PDF Download ePub
RESEARCH ARTICLEDOI: 10.2174/0118750362358444250120070327 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. Multimodal Skin Cancer Prediction: Integrating Dermoscopic Images and Clinical Metadata with Transfer Learning Volume: 18 (2025): e18750362358444 [Electronic Publication Date: January 28, 2025] Ramya Panneerselvam, Sathiyabhama Balasubramaniam, Vidhushavarshini Sureshkumar, Vinayakumar Ravi and Siti Sarah Maidin Abstract View Fulltext HTML PDF Download ePub


RESEARCH ARTICLEDOI: 10.2174/0118750362429534250911103350 All articles published in Open Bioinformatics Journal are now available worldwide under an open-access license. No specific permission is required to reuse all or part of the Open Bioinformatics Journal article, including figures and tables. Any part of an article published under a Creative Commons CC BY license may be copied without permission as long as the original material is clearly referenced. https://openbioinformaticsjournal.com/open-access-policy.php. NOTE: Please note that this article is currently in the 'Early view' stage and is not the final 'Version of Record'. While it has been accepted, copy-edited, and formatted, however, it is still undergoing proofreading and corrections by the authors. Therefore, the text may still change before the final publication. Although 'Early view' may not have all bibliographic details available, the DOI and the year of online publication can still be used to cite them. The article title, DOI, publication year, and author(s) should all be included in the citation format. Once the 'Final Version of Record' becomes available the 'Early view' will be replaced by that. In Silico Identification of Potential PD-L1 and VISTA Inhibitors in Ovarian Cancer: A Computational Approach Combining Virtual Screening and Molecular Dynamics Simulations Volume: 18 (2025): e18750362429534 [Electronic Publication Date: September 15, 2025] Narjisse Ahmadi, Mohammed Hakmi, Zainab Gaouzi, Naima Elhafidi and Azeddine IBRAHIMI Abstract View Fulltext HTML PDF

RESEARCH ARTICLEDOI: 10.2174/0118750362429534250911103350

In Silico Identification of Potential PD-L1 and VISTA Inhibitors in Ovarian Cancer: A Computational Approach Combining Virtual Screening and Molecular Dynamics Simulations

Volume: 18 (2025): e18750362429534
[Electronic Publication Date: September 15, 2025]

Narjisse Ahmadi, Mohammed Hakmi, Zainab Gaouzi, Naima Elhafidi and Azeddine IBRAHIMI

Abstract View Fulltext HTML PDF

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Three Journals Receive Impact Factors

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Identification of Diagnostic and Prognostic Biomarkers in Nasopharyngeal Carcinoma using Integrated Transcriptomics and Elastic Net Survival Analysis

A Comprehensive Review of Blood Malignancy Detection in Microscopic Blood Cell Images Utilizing Complete Leukocyte Count Data

Tool FindCrispr: An Accurate Identification of Crisprs

Convolutional Neural Network-based Multi-Classification of Skin Disease with Fine-Tuned ResNet50 and VGG16

A Mathematical Model for Predicting Nearest Neighbor in Diabetes Diagnosis

A Review of Deep Learning-based Multi-modal Medical Image Fusion

Corrigendum to: Advanced Machine Learning Techniques for Prognostic Analysis in Breast Cancer

In Silico Study of Dibenzylidene Cyclohexanone-Based Curcumin Analogs as Potential Inhibitors of Breast Cancer Receptor Proteins

Characterizing and Evaluating Cell Specialization Through the Gini Index of Gene Expression: A TCGA Normal vs. Tumor Case Study

Enhancing Early Diagnosis of Type II Diabetes through Feature Selection and Hybrid Metaheuristic Optimization Techniques

iCDRET: A Dynamic Cyber Risk Estimation Technique for Intelligent Cyber-physical Systems in PCS

A Dual CT Image Denoising Approach using Guided Filter and method-based Noise in the NSST Domain

Balancing Accuracy and Recall in Hebbian and Quantum-inspired Learning Models

Patterns of Transposable Element Distribution around Chromatin Ligation Points Revealed by Micro-C Data Analysis

Exploring Camptothecin Derivatives from the Chinese Tree of Camptotheca acuminata as Breast Cancer Protease Inhibitors: Insights from Multi-Scale Computational Analysis

Bioinformatics and System Biology Approach to Identifying the Influence of COVID-19 on Patients with Osteoarthritis

In Vitro and In Silico Study of Nardostachys Jatamansi DC for Cognitive Impairment Related Conditions

Evaluating Deep Learning Models for Object Detection in Kirby-Bauer Test Result Images

Predictive Analysis of Parkinson's Disease Using Machine Learning

In silico Evaluation of Potential Bioactive Peptides of Phycoerythrins from Selected Rhodophytes

Enhancing Brain Tumor Segmentation using Berkeley Wavelet Transformation and Improved SVM

Deep Learning-based Staging of Throat Cancer for Enhancing Diagnostic Accuracy Through Multimodal Data Integration

Ensemble-based Heart Disease Diagnosis (EHDD) using Feature Selection and PCA Extraction Methods

Advanced Machine Learning Techniques for Prognostic Analysis in Breast Cancer

Multimodal Skin Cancer Prediction: Integrating Dermoscopic Images and Clinical Metadata with Transfer Learning

In Silico Identification of Potential PD-L1 and VISTA Inhibitors in Ovarian Cancer: A Computational Approach Combining Virtual Screening and Molecular Dynamics Simulations

Press Release

Bentham Is Proud To Announce Collaboration With Elsevier

Three Journals Receive Impact Factors

The Nursing Journal Directory Indexes Bentham Journal, The Open Public Health Journal

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